During the recent years 3-D imaging has become a standard tool for diagnosis and planning in the clinics using well-known imaging modalities as CT or MRT. The integration of those image during an intervention is difficult and requires various registration techniques. A solution that has emerged in recent years is the use of fluoroscopic C-arm systems which are highly common in the interventional field for reconstructing 3-D images. The workflow can be seen in the following three videos from one of our clinical cooperations (Klinikum Coburg GmbH): The general goal of my research topics is to enrich that workflow for mainly cardiac applications by providing high quality, fast and reliable algorithms for the 3-D reconstruction of challenging subjects. Of course this work is highly interdisciplinary and requires techniques and concepts from the complete field of medical image processing. In the following an overview of the detailed research topics is provided.