Techn. Fakultät Willkommen am Institut für Informatik FAU-Logo

Dipl.-Ing. Marc Aubreville

Researcher in the Computer Vision (CV) group at the Pattern Recognition Lab of the Friedrich-Alexander-Universität Erlangen-Nürnberg

Classification of cancerous and physiological tissue in confocal lasermicroendoscopy (CLE) images

The goal of this project is to detect cancerous tissue in confocal lasermicroendoscopy (CLE) images of the oral cavity and the vocal cord. The current treatment of these diseases is a histological analysis of specimen and a surgical resection, which has a rather high long-term survival rate, or radiation therapy with a lower survival rate. An early detection of cancerous tissue could lead to a lowered complication rate for further treatment, as well as a better overall prognosis for patients. Further, an in-vivo diagnosis during operation could narrow down the area for the necessary surgical excision, which is especially beneficial for cancer of the vocal cords.

Detection and classification of cells in digital histology images

Identification and counting of cells is a standard task in histopathology. Due to the large overall cell count on histological slides and the sparse prevalence of some relevant cell types, counting for sufficient statistics is a tedious task and prone to a significant error in assessment.

Our goal is to develop a more objective and accurate, automatized approach to histological mitosis counting by assisting pathologist in the selection of fields with the highest mitotic counts and more constant parameter of mitotic figure identification.